Bio 111B

Study Questions 6

CIRCULATION AND GAS EXCHANGE

1. What causes O2 to move from the alveoli into the pulmonary capillaries?

2. What attributes of the respiratory membrane contribute to the efficiency of gas transport across the membrane?

3. In what form or how is most O2 transported in the blood? What about CO2?

4. The graph below shows O2-dissociation curves for hemoglobin at two different pH values.

 

a. On average, how many molecules of O2 are attached to hemoglobin at pH 7.4 at 40 mm Hg pO2? What about at 25 mm Hg pO2?

b. How does the shift to the right from pH 7.4 to pH 7.2 alter O2 affinity of the hemoglobin?

c. How is this altered affinity important to organisms?

d. What would cause a pH difference between resting and active muscle?

 

5. Llamas live at high altitudes where atmospheric pO2 is approximately 85 mmHg compared to 160 mm Hg at sea level. The hemoglobin molecule of these animals is somewhat different from human hemoglobin; it is able to pick up O2 at lower pO2. How would the O2-hemoglobin dissociation curve for llama hemoglobin compare to the O2-dissociation curve for human hemoglobin?